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MATERNAL SCREEN-1ST TRIMESTER DUAL

  2550

Parameters covered : 1

Parameters

1.  PAPPA

 

Reporting Time

up to 48 Hrs

Speciman Type

PLAIN

Blood Home Collection Service

Available

Precautions

Recommennded for 9 to 13.6. weeks with completely filled maternal TRF with barcode and USG report.History is mandatory.

Test Details

The MATERNAL SCREEN-1ST TRIMESTER DUAL test is a prenatal screening test conducted during the first trimester of pregnancy. It assesses the risk of specific chromosomal abnormalities, particularly Down syndrome (Trisomy 21), in the developing fetus.

The MATERNAL SCREEN-1ST TRIMESTER DUAL test, also known as the Dual Marker Screening test, is a prenatal screening test conducted during the first trimester of pregnancy. It assesses the risk of specific chromosomal abnormalities, particularly Down syndrome (Trisomy 21), in the developing fetus. This test typically includes the following components:

Nuchal Translucency Ultrasound: An ultrasound examination is performed to measure the thickness of the fluid-filled space at the back of the developing fetus's neck, known as nuchal translucency. Abnormal thickness can indicate an increased risk of certain chromosomal abnormalities.

Blood Tests: Two blood tests are conducted:

a. PAPP-A (Pregnancy-Associated Plasma Protein-A): This blood test measures the levels of PAPP-A in the maternal blood. Abnormal levels can be associated with an increased risk of chromosomal abnormalities.

b. Free Beta-hCG (Human Chorionic Gonadotropin): This blood test measures the levels of free beta-hCG in the maternal blood. Abnormal levels can also be associated with an increased risk of chromosomal abnormalities, particularly Down syndrome.

The results of these components, along with factors such as maternal age and gestational age, are combined to provide a risk assessment for chromosomal abnormalities, especially Down syndrome. It's important to note that the MATERNAL SCREEN-1ST TRIMESTER DUAL test is a screening test, not a diagnostic test. Abnormal results suggest an increased risk, but further diagnostic tests, such as amniocentesis or chorionic villus sampling (CVS), may be recommended for a definitive diagnosis if the results are concerning.

 

Blood Sample: A healthcare provider collects a blood sample from the pregnant individual, typically from a vein in the arm, using a needle and a syringe.

Ultrasound: In addition to the blood test, an ultrasound is performed to measure the thickness of the fetal neck's skin (nuchal translucency).

Laboratory Analysis: The blood sample is sent to a laboratory for analysis. The laboratory assesses the levels of specific substances in the blood.

Fasting or special preparation is generally not required for the MATERNAL SCREEN-1ST TRIMESTER DUAL test. You can typically eat and drink normally before the test.

You may feel a brief pinch or discomfort when the needle is inserted for the blood sample. The ultrasound is painless.

Normal results mean that the risk of chromosomal abnormalities is within the expected range for the pregnancy.

Abnormal results indicate an increased risk of chromosomal abnormalities, particularly Down syndrome. However, it's important to note that this test provides a risk assessment, not a definitive diagnosis. Further diagnostic tests, such as amniocentesis or chorionic villus sampling (CVS), may be recommended if the results are concerning.

The MATERNAL SCREEN-1ST TRIMESTER DUAL test is generally considered safe. Risks are minimal and may include:

Mild bruising at the blood sample site.

Rarely, fainting or lightheadedness during or after the blood draw.

The MATERNAL SCREEN-1ST TRIMESTER DUAL test may also be known as:

First-trimester maternal serum screen

Dual marker screening test

First-trimester prenatal screening test

Pregnancy Test

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